Vehicle for the administration of drugs by IV infusion
Severe dehydration, fluid replacement in trauma, surgery, anaesthesia (preferably use of Ringer lactate for these indications)
Forms and strengths
100 ml, 250 ml, 500 ml and 1000 ml bottles or bags
Composition
Isotonic solution of sodium chloride (0.9 g per 100 ml) for infusion
Ionic composition:
sodium (Na+) 150 mmol (150 mEq) per litre
chloride (Cl–) 150 mmol (150 mEq) per litre
Contra-indications, adverse effects, precautions
Use with caution in patients with hypertension, heart failure, oedema, ascites due to cirrhosis, renal impairment and other conditions associated with sodium retention.
May cause: pulmonary oedema in the event of too rapid infusion or infusion of excessive amounts.
Do not use as vehicle for the administration of amphotericin B (incompatibility): use only 5%glucose solution.
Remarks
After infusion, NaCl 0.9% remains in the intravascular compartment for 1 to 2 hours.
For correction of hypovolaemia due to haemorrhage, administer 3 times the lost volume only if:
blood loss does not exceed 1500 ml in adults;
cardiac and renal function are not impaired.
0.9% sodium chloride solution may be used to prevent hypotension induced by spinal anaesthesia.
For external use: sterile 0.9% sodium chloride solution is used for cleansing of non-infected wounds, wound irrigation, eye cleansing (conjunctivitis, eye irrigations), nasal lavage in the event of obstruction, etc.