Symptomatic treatment of persistent diarrhoea in adults with HIV infection, in combination with rehydration
Forms and strengths
2 mg capsule or tablet
Dosage
Adult: 4 mg (2 capsules), then 2 mg (1 capsule)after each loose stool, without exceeding 16 mg daily (8 capsules daily).
Duration
According to clinical response
Contra-indications, adverse effects, precautions
Do not exceed indicated doses. Do not administer to children.
Do not administer to patients with bloody diarrhoea, ulcerative colitis, diarrhoea due to antibiotics. May cause:constipation, allergic skin reactions, drowsiness, dizziness.
In the event of overdosage, treat with naloxone.
Pregnancy: no contra-indication
Breast-feeding: no contra-indication
Remarks
Rehydration is essential and must be adapted to the severity of diarrhoea.
Loperamide is not included in the WHO list of essential medicines.